iodination

CI is used as an iodination reagent, often upon reaction with base.

It is the product of an iodination between iodine and N,N-dimethylaniline.

Bromination and iodination work best, though this reaction does not preserve the stereochemistry of the alcohol.

Potassium iodate is sometimes used for iodination of table salt to prevent iodine deficiency.

"For example, if not for iodination (fortification) of table salt, many people would be walking around with goitre," he said.

The direct iodination with I is employed with unsaturated substrates:

Free-radical iodination is usually not possible because iodine is too unreactive to form a radical.

- May inhibit iodination of tyrosyl residues in thyroglobulin.

As applied to electrophilic iodination, Selectfluor reagent activates the I bond.

A representative electrophilic iodination reagent is iodine monochloride.

It has eliminated endemic cretinism in most developed countries, and some governments have made the iodination of flour, cooking oil, and salt mandatory.

It is also formed as a by-product in thallium-promoted iodination of phenols with thallium(I) acetate.

The food dye erythrosine can be synthesized by iodination of another dye called fluorescein:

Researchers have created an avidin with reversible binding characteristics through nitration or iodination of the binding site tyrosine.

Thyrostatics are believed to work by inhibiting the iodination of thyroglobulin by thyroperoxidase, and, thus, the formation of tetra-iodothyronine (T).

Organoiodine compounds are prepared by numerous routes, depending on the degree and regiochemistry of iodination sought and the nature of the precursors.

The iodination of specific tyrosines yields monoiodotyrosine (MIT) and diiodotyrosine (DIT).

Hydrazones are reactants in hydrazone iodination, the Shapiro reaction and the Bamford-Stevens reaction to vinyl compounds.

In these studies both the kinetics of the reaction and the preparative conditions for the iodination of strongly deactivated compounds, such as benzoic acid and 3-nitrobenzotrifluoride, were investigated.

Isopropyl iodide is prepared by iodination of isopropyl alcohol using hydrogen iodide or, equivalently, with a mixture of glycerol, iodine, and phosphorus.

Oxidative halogenation can be promoted by CAN as an in situ oxidant for benzylic bromination, and the iodination of ketones and uracil derivatives.

The mechanism for iodination is slightly different: iodine (I) is treated with an oxidizing agent such as nitric acid to obtain the electrophilic iodine (2 I).

Free iodine, slowly liberated from the poviodine-iodine (PVP-I) complex in solution, kills eukaryotic or prokaryotic cells through iodination of lipids and oxidation of cytoplasmic and membrane compounds.

Anti-thyroid peroxidase (anti-TPO) antibodies are specific for the autoantigen TPO, a 105kDa glycoprotein that catalyses iodine oxidation and thyroglobulin tyrosyl iodination reactions in the thyroid gland.

After an unusual hydrazone iodination that also involved iodination alpha to a carbonyl group and elimination of HI, fully conjugated vinyl iodide 28 was produced in an unexpected dehydrogenation.