It may be the case that these structures are involved in intracellular transport, which would provide a unique example of convergent evolution on the cellular level.
Instead, they cause incorrect folding (disrupting function) or disable intracellular transport.
They may also play a role in intracellular transport to axons and dendrites.
BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
The focus of Traffic is Signal transduction (intracellular transport) in health and disease, for both mammalian and non-mammalian biological systems.
HEAT repeats form a rod-like helical structures which are involved in intracellular transport.
It was found that substituting Asp-513 with Glu-513 interferes with posttranslational modification and intracellular transport of alpha-glucosidase's precursor.
Actin and Myosin are for intracellular transport and cytoskeletal movement, so I don't see how this is relevant.
However, the exact role of this protein in intracellular transport of bile acids and cytoprotection was undefined.
Within the cell membrane, cholesterol also functions in intracellular transport, cell signaling and nerve conduction.