Maintenance therapy with the drug (versus intermittent or sporadic therapy) lessens the likelihood of developing antibodies to infliximab which are known to reduce the efficacy of the drug.
It is difficult to determine the contribution of intermittent therapy to the high response rate obtained in this uncontrolled study.
Considering the short lasing benefit of mass drug administration one modification has been to repeat mass drug administrations which has led to the development of intermittent preventive therapy.
Deaths in malaria can be sharply and cost-effectively reduced by use of insecticide-treated bednets, prompt artemisin-based combination therapy, and supported by intermittent preventive therapy in pregnancy.
Although intermittent therapy might be more acceptable to some women, this might be less effective than continuous regimens.
Only severe cases may require intermittent therapy.
Sulfadoxine/pyrimethamine has been used in mass drug administrations as well as in intermittent preventive therapy.
Because less medication would be taken, the intermittent therapy presumably would reduce unwanted side-effects.
To Dr. Fauci, the greatest potential benefit of intermittent therapy would be in providing Africans an easier and more affordable way to take the drugs that are widely used in rich countries.
Your doctor may prescribe an antiviral drug for you to keep on hand in case you have another flare-up; this is called intermittent therapy.