Fas-associated phosphatase is a molecule that inhibits the effect of Fas ligand to make cells initiate apoptosis.

One of the damaging results of excess calcium in the cytosol is initiating apoptosis through cleaved caspase processing.

After birth these cells usually die, a process that is triggered by a decline in nerve growth factor (NGF)which initiates apoptosis (cell death).

This domain does not correspond to a known caspase recruitment motif or death sequence domain, but is required to initiate apoptosis.

This causes the activation of caspase-3 through caspase-9, and initiates apoptosis without the formation of an apoptosome or cytochrome c release.

Under high levels of cellular stress, p53 initiates apoptosis instead.

The osteoclast initiates apoptosis and dies, leading to an overall decrease in the breakdown of bone.

It can initiate apoptosis, the programmed cell death, if DNA damage proves to be irreparable.

However it is a widely believed that the protein is involved in tumour suppression by decreasing cell growth through initiating apoptosis.

Additional to these effects, another target of pyocyanin is caspase 3-like proteases which can then go on to initiate apoptosis and necrosis.