The toxic actions of MIT on developing neurons occurs at much lower concentrations than those inducing lethal injury (1-3 micromolar).
Lap belts can induce severe injury or death by crushing vertebrae, the spinal cord and internal organs as occupants are thrown forward in some frontal crashes.
There is only so much conditioning that one can do to obtain an edge without inducing injury.
We have examined the hypothesis that the release of tissue type plasminogen activator may play a prominent role in endothelin induced gastric mucosal injury.
Figure 4A shows the effect of CV-6209 on the endothelin induced gastric mucosal injury.
These cytokines may affect the functions of immunocompetent cells to induce colonic injury or induce the lysis of colonic epithelial cells directly.
The implication is that cholesteryl esters may play an important role in the pathogenesis of alcohol induced pancreatic injury.
It is unclear how phenacetin induces injury to the kidney.
Cleaved forms of CRMPs have also been linked to neuron degeneration after trauma induced injury.
Several mechanisms are responsible for either inducing hepatic injury or worsening the damage process.