The most important disadvantage is that the water is very cold, in spite of the high temperatures of the city, all the year round.

Furthermore, viruses may spread out to other organs after intraarticular injection and this will be an important disadvantage.

An important disadvantage to this method is that it requires the organism to use much more energy then the adaption below.

Although we may in this way gain in explanatory capacity, there are several important disadvantages associated with a participant observation study.

But this steering method has some important disadvantages in the newer vehicles that most people now drive.

Mr. Bush and his allies have faced an important rhetorical disadvantage, particularly from the right.

However, the mobile phone also has important disadvantages compared to the PC:

The limited ammunition capacity was an important disadvantage.

These limits may have created important disadvantages over millions of years.

At the same time, the new rules have one important disadvantage.