A system of blood and blood vessels now develops at the point of the newly forming placenta, growing near the implantation site.

Several days later, chorionic villi in the forming placenta anchor the implantation site to the uterus.

It also may call for examination of potential alternate implantation sites.

The function of the implantation site intermediate trophoblast is to anchor the placenta to the maternal tissue.

IFNγ dilates and thins the walls of maternal spiral arteries to enhance blood flow to the implantation site.

This allows the lining of the uterus to be cleared out properly, and thus provide a good implantation site for the new fetus to settle on.

Further, only 2 of the 6 mice treated had noticeable tumors around the implantation site.

The pre-operative targeting of proper implantation sites can be accomplished via the indirect and direct methods.

The pain is caused by prostaglandins released at the implantation site, and by free blood in the peritoneal cavity, which is a local irritant.

Placental-site trophoblastic disease is an extremely rare tumor arising from the placental implantation site and resembles an exaggerated form of syncytial endometritis.