Prof Kay said: 'It does not touch any human enzymes at all.'

In any event, resveratrol proved to be a potent activator of the human enzyme.

But such drugs are some way off, because they must avoid harming the equivalent human enzymes.

For example, some alkenes are toxicated by human enzymes to produce an electrophilic epoxide.

After joining Merck, he immediately applied his faith in the notion that important therapies could be based on drugs that would manipulate human enzymes.

Many of these inhibitors target a human enzyme and aim to correct a pathological condition.

The human enzyme efficiently acts on progesterone, androstenedione, 17alpha-hydroxyprogesterone and testosterone to 5beta-reduced metabolites.

Further, human drug-metabolizing enzymes are typically activated through the engagement of nuclear receptors.

Despite its bovine origin, the ADA worked exactly as the human enzyme does.

The specific activity of highly purified human enzyme is 890,000 units/mg.