WR is associated with abnormalities in bone maturation, and lipids and hormone metabolism.
This enzyme participates in c21-steroid hormone metabolism and androgen and estrogen metabolism.
Congenital hypothyroidism is very rare, accounting for approximately 0.2% of cases, and can have several causes such as thyroid aplasia or defects in the hormone metabolism.
There are a number of rare but well-described genetic conditions affecting parathyroid hormone metabolism, including pseudohypoparathyroidism, familial hypocalciuric hypercalcaemia, and autosomal dominant hypercalciuric hypocalcaemia.
Blocking enzymes that are involved in hormone metabolism.
This enzyme participates in 3 metabolic pathways: bile acid biosynthesis, c21-steroid hormone metabolism, and androgen and estrogen metabolism.
This enzyme participates in bile acid biosynthesis and c21-steroid hormone metabolism.
This enzyme participates in c21-steroid hormone metabolism.
The classes of CYPs most often investigated in non-human animals are those either involved in development (e.g., retinoic acid or hormone metabolism) or involved in the metabolism of toxic compounds (such as heterocyclic amines or polyaromatic hydrocarbons).
It is therefore suspected of playing a role in hormone metabolism, drug addiction and circadian rhythms.