The carriers of the high-risk genes have a tenfold increased risk of myopia.

You're not supposed to get a high-risk gene.

The participants in the study with the high-risk gene also had deficits in areas of the brain involved in moderating emotion, supporting many earlier studies finding similar gene-related differences.

Some breast-cancer organizations oppose such testing, saying it is premature, since it is not yet known what different mutations of the gene mean, what is the best course of action for women found to have the high-risk gene, or how to protect the confidentiality of test results.

Indeed, low penetrance genes cannot be easily tracked through families, as is true for dominant high-risk genes.

Identifying high-risk genes provides insight into breast cancer etiology and allows the development of preventive interventions for affected populations.