The transgene was maintained in the heterozygous state by crossing the rdta mice to C57BL/6J mice.

A single copy of the EDNRB mutation, the heterozygous state, produces an identifiable and completely benign spotted coat color called frame overo.

Some alleles, such as sash produce white spotting alone, while others affect the health of the animal even in the heterozygous state.

Instead, the MATP mutation is visible the heterozygous state, but more so in the homozygous state.

It should be noted, however, that if markers are used in the heterozygous state, the expected grain count is halved since the other half is expected to overlie the unmarked, and therefore unscored normal homologues.

Compound heterozygosity in medical genetics is the condition of having two heterogeneous recessive alleles at a particular locus that can cause genetic disease in a heterozygous state.

Recessive lethal "balancer chromosomes" carrying visible genetic markers can be used to keep stocks of lethal alleles in a heterozygous state without recombination due to multiple inversions in the balancer.

Frost suggests the heterozygous state enhanced reproductive success by enabling adaptation to the mental tasks of market-orientated occupations.

In the case of LWS, a single copy of the EDNRB mutation, the heterozygous state, produces an identifiable trait, but with a very different outcome from the homozygous state.

Similarly to the spectrin mutations, band 4.1 mutations cause a mild haemolytic anaemia in the heterozygous state, and a severe haemolytic disease in the homozygous state.