Hepatic dysfunction was defined as greater than twice normal activity of at least two hepatic enzymes.
Bromazepam is reported to be metabolized by a hepatic enzyme belonging to the Cytochrome P450 family of enzymes.
This metabolite is then free to react with key hepatic enzymes, therefore damaging hepatocytes.
Others may have symptoms and signs related to right ventricular failure, such as lower extremity edema, or liver congestion with elevated hepatic enzymes.
Clear conclusions with universal validity are difficult to draw, since different ethnic groups show considerable genetic polymorphism for the hepatic enzymes responsible for ethanol detoxification.
An extract of Syzygium aromaticum represses genes encoding hepatic gluconeogenic enzymes.
Clinical studies in patients with normal liver function have shown that there is no elevation in the hepatic enzymes with the use of levamlodipine.
It can also cause elevations in hepatic enzymes such as gamma-glutamyl transferase and alkaline phosphatase.
Primidone, carbamazepine, phenobarbital and phenytoin are among the most potent hepatic enzyme inducing drugs in existence.
Other nonspecific findings include monocytosis, occurring in the majority of sarcoidosis cases, increased hepatic enzymes or alkaline phosphatase.