His family, friends, and colleagues are greatly saddened by his passing.

"I am greatly saddened by this terrible news," he said.

She knew that much of the blood spilled was his fault and this greatly saddened her.

Greatly saddened, Zeeshan takes a steak knife into the bathroom to kill himself.

Hayes was greatly saddened by his wife's death in 1889.

The statement added that officials were "greatly saddened" by what happened and wished all the best to the families.

I know that the Turkish authorities are greatly saddened by recent events.

I was greatly saddened by your story about Osaka, but in a way uplifted.

"I was greatly saddened to hear of your husband's death."

I am greatly saddened to hear of the king's unfortunate demise.