This proved to be the greatest technological breakthrough since the introduction of mid-engined cars.

The electrified steel guitar made its greatest breakthrough into country music.

It seemed an unlikely site for the greatest scientific breakthrough of the twenty-first century.

Perhaps the greatest breakthrough was the revolutionary concept of breakfast served all day.

Both nations stand on the brink of the greatest breakthrough in curbing the arms race since the nuclear age began.

Word processing is perhaps the greatest breakthrough for disabled students.

The swordsmen had decided that polo was the greatest breakthrough since the invention of puberty.

For better or for worse, the greatest technological breakthrough in history is still to come.

That is the greatest breakthrough as we work towards a social Europe.

Tell us about the greatest scientific breakthrough of our time.