Aleksei Kovalev extended his goal-scoring streak to four games at 7:53 of the first, giving the Penguins a 1-0 lead.
Jeremy Roenick, who has 33 goals this season, extended his goal-scoring streak to four games with the night's first goal.
He finished the regular season with a five-game goal-scoring streak.
Lemieux, who is expected to return soon, was on a five-game goal-scoring streak, one short of the Devils' team record.
Chicago's Tony Amonte had his goal-scoring streak stopped at three games.
It brought Kariya's goal-scoring streak to four games.
With his goal, the right wing increased his goal-scoring streak to four games.
Zigmund Palffy failed to get off one shot and saw his seven-game goal-scoring streak come to an end.
Messier's goal-scoring streak resumed early when he found himself the recipient of a gift puck.
She set Mercyhurst records with a 13-game goal-scoring streak and 16-game point-scoring streak.