Nowell synthesized the evolutionary view of cancer in 1976 as a process of genetic instability and natural selection.
An increase in ipsilateral and contralateral breast cancers secondary to genetic instability.
Calazar explained, "It could have been a result of extreme genetic instabilities still inherent in the race.
Therefore they possessed a greater genetic instability, and with it a tendency to a more extreme form of mutation.
The repair of such a break is critical because otherwise the chromosome may snap in two, plunging the cell into genetic instability, uncontrolled growth and cancer.
Chromosomal instability resulting from dysfunctional caretaker genes is the most common form of genetic instability that leads to cancer in humans.
The changes may cause increased risk of cancers or genetic instability in future generations.
As explained above, genetic instability means that the Traminers should be regarded as a family of related clones, rather than distinct varieties.
He said chemicals could influence a person's baseline level of genetic instability, making DNA alterations more or less likely at any given time.
Defects in this segregation can cause genetic instability, a condition which is highly associated with tumorigenesis.