On entering the thymus, they undergo a programme of proliferation, T-cell receptor (TCR) gene rearrangement, differentiation and repertoire selection.

B-cells form in the bone marrow and undergo gene rearrangement in order to develop B-cell receptors (BCRs) that bind to a specific antigen.

Although, when two besotted humans had the temerity to elbow me in the ribs, I indulged in some harmless gene rearrangement.

The gene rearrangement and subsequent regeneration incident to conjugation and fission put him out of the running for a long time.

This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2.

Like the chimpanzee, changes were on the level of gene rearrangements rather than single mutations.

Immature thymocytes each make distinct T-cell receptors by a process of gene rearrangement.

An important discovery in comparative genomics is that local gene rearrangements happen quite often during evolution, disrupting gene order in gene clusters [ 13].

By repairing DNA, these proteins play a role in maintaining the stability of the human genome and prevent dangerous gene rearrangements that can lead to hematologic and other cancers.

Within Heterobranchia, gene order seems relatively conserved, and gene rearrangements are mostly related with transposition of tRNA genes.