Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.
A conditional knockout allows gene deletion in a tissue or time specific manner.
This sub-section illustrated the condition-dependent effect of gene deletions on the metabolic genotype-phenotype relation.
This partial gene deletion seems to be the case with some members of the two families studied.
The problem comes when one member of a couple shows the gene deletion and the other does not.
Does the gene deletion that marks the syndrome impair an older set of instructions for brain development, while leaving a newer language circuit intact?
Determining the effect of gene deletion is a fundamental approach to understanding gene function, providing an unparalleled resource for the scientific community.
This measure is important when making claims about the target of a small molecule, effects of gene deletion or specificity of a drug.
This "facilitates functional analysis by site-specific gene deletion."