Almost all cases have resulted from new mutations, and occur in people with no history of the disorder in their family.
Well, we know that variations of a given species arise from mutations caused by various agencies.
For example, perturbations can come either from the environment or from mutations.
Clinically these are distinct but appear to arise from mutations in the same gene.
The multiple types of this syndrome result from mutations occurring in different genes.
Some species are said to have evolved suddenly from single mutations without transitional species.
There are different short-term and long-term effects that can arise from mutations.
All disorders within this group are monogenetic, meaning they come from mutations of a single gene.
Other cases may result from new mutations in the gene.
Some ED conditions are only present in single family units and derive from very recent mutations.