Recent research has shown that some female carriers of the disease may become symptomatic with the disorder later in life, suffering high ammonia levels.

If a female carrier is operating on her normal X she will not show symptoms.

A female carrier will pass the affected AR gene to her children 50% of the time.

Typically, a female carrier will be unaware they carry a mutation until they have an affected son.

This may give rise to mild symptoms in female 'carriers' of X-linked genetic disorders.

Females are rarely affected; female carriers tend to have a relatively mild expression of the disease if they show symptoms at all.

The sons of female carriers are at 50% risk of being affected with the syndrome.

The daughters of female carriers are at 50% risk of being carriers themselves.

Some female carriers become symptomatic later in life in times of metabolic stress.

However, such a procedure would additionally require an artificial womb or a female gestational carrier.