As the vote neared, fatigue and testiness had set in on the floor.

And holding and clinching is common, particularly when fatigue sets in towards the end of latter rounds.

Confusion and fatigue can set in, hampering a person's ability to understand what's happening and make intelligent choices to get to safety.

Now, just by talking to the doctors, they say this is when the fatigue sets in.

"The fatigue sets in much quicker than normal," Little said.

His nerves were singing with tension, but he knew that if the warriors took too long, fatigue would surely set in.

Then, if a pandemic lasts for weeks, fatigue will set in.

The fatigue often sets in during the middle of a course of treatment and can last for weeks after treatment ends.

For example, a lack of proper lighting can strain eyes; if this occurs, fatigue can set in.

Three days later a red circle the size of a quarter appeared, and a bone-deep fatigue set in.