Even a very low false-positive rate will result in so many false alarms as to make such a system useless in practice.
This more sensitive filter yielded only 2 genes out of 4,608, indicating a low and satisfactory false-positive rate.
If left unaccounted for, this could lead to a high false-positive rate.
As in most experiments, it is important to first estimate the false-positive rate for this type of comparison between brain regions.
In other words, ignoring the qualitative calls increased the false-positive rate by a factor of 20.
To determine all this information, including estimating the false-positive rate and testing the selection criteria, required less than ten minutes.
This offers an 85-88% sensitivity and 5% false-positive rate for Down Syndrome.
The 1% false-positive rate can be reduced by a factor of ten by adding only about 4.8 bits per element.
The false-positive rate was 18 percent, of which half were corrected on a follow-up sonogram.
It is more relevant to optimize with respect to false-positive and false-negative rates.