Our challenge is to make explicit the basis for the intuitions and judgments that happen there and to make applicable the results of experimental interventions gained under more constrained conditions.
The order of experimental and control interventions can also be fixed by the researcher.
Schechter's work has included the study of experimental interventions that may lead to changes of trauma-associated mental representations that can help intergenerational cycles of violence.
This can enable a better understanding of mechanistic changes to specific cell lineages resulting from a particular experimental intervention.
In surgery, new approaches are often characterized as "innovative therapy" instead of experimental interventions warranting enhanced information disclosure and prior ethical review.
He suggests a "government commission, which can come up with policies and guidelines that would govern experimental and innovative medical interventions."
However, even at this stage, much might be learned from some experimental intervention trials, both about aetiology and prevention.
For example, RCTs may be stopped early if an intervention produces "larger than expected benefit or harm," or if "investigators find evidence of no important difference between experimental and control interventions."
Once a patient reaches the endpoint, he or she is generally excluded from further experimental intervention (the origin of the term endpoint).
A study of 159 randomized clinical trials found a significant association between authors' financial competing interests and their favorable conclusions about an experimental intervention [6].