Loss of REM sleep has been noticed during various natural and experimental infections.
In 1905, a fourth rule was added: The organism must be isolated again from the experimental infection.
Niclosamide (2 mg) was very effective against experimental infection in human.
In large doses it was effective against experimental infections in animals, and some related compounds called sulphones were better.
However, instances of reduced weight loss and decreased production of eggs are observed in experimental infections.
One possible experimental infection has been reported with Plasmodium eylesi.
Much of the information concerning S. vulgaris has been derived from experimental infection of foals.
In heavy experimental infections the most severe signs have appeared at 6-12 weeks after infection when egg-laying is maximal.
His assumption, however, has been neither confirmed by positive findings in the field nor by experimental infection.
Three research groups have reported experimental infection of mice with Blastocystis produces intestinal inflammation.