Some experiments just published in Current Biology may have identified one such case, although the results aren't as clear-cut as some press accounts have suggested.
Loewi's famous experiment, published in 1921, largely answered this question.
For an experiment published in 1960, he challenged subjects to identify a rule applying to triples of numbers.
This model of the chemical reactions makes several predictions that were examined in experiments published by Jerry Goodisman in 2001.
Solomon Asch took the paradigm from his experiment published in 1951 and applied it to his subsequent research experiments.
These experiments, published in 1941, led them to propose a direct link between genes and enzymatic reactions, known as the "one gene, one enzyme" hypothesis.
In an experiment published in 2005, researchers had college students who described themselves as socially awkward in high school recall one of their most embarrassing moments.
One experiment published in 1862 described the first nucleophilic displacement of chlorine by fluorine in benzoyl chloride.
The dramatic effect of the steps was observed in the ensuing experiment, published in 1974.
Loewi's experiments, published in 1921 [1], finally settled the issue, proving that synaptic transmission was chemical.