They do not exchange heat, work or matter with their environment.
A greenhouse is an example of a closed system exchanging heat but not work with its environment.
Whether a system can exchange heat, work, or both is dependent on the property of its boundary.
Large body-size would, in fact, isolate them from their thermal environment because they would exchange heat at lower rates.
In order to maintain a stable body temperature, they exchange heat with their external environment.
As the system is thermally isolated, it cannot exchange heat with its surroundings.
Your nose is designed to exchange heat with incoming (or outgoing gases).
The incoming crude oil is preheated by exchanging heat with some of the hot, distilled fractions and other streams.
Cooling was done with Freon circulating within the machine and exchanging heat to an external chilled water supply.
Suppose these appliances could intelligently exchange heat to minimize power consumption?