Often it is desirable to express eukaryotic genes in prokaryotic cells.
Tentatively, eukaryotic genes are governed by rules biased toward many canalyzing inputs per gene.
Traditionally, Escherichia coli was the species of choice to express eukaryotic genes, since it was well understood and easy to work with.
But some important eukaryotic genes have no obvious predecessors in either the archaean or bacterial lines.
Therefore it was long assumed that eukaryotic genes were randomly distributed across the genome due to the high rate of chromosome rearrangements.
Approximately 1% of eukaryotic genes code for helicases.
The split gene structure was found to be common to most eukaryotic genes.
This shift means that we can test if there is a bias in sampled eukaryotic genes.
It is not used in cytosolic protein synthesis of eukaryotes, where eukaryotic nuclear genes are translated.
Spliceosomal introns often reside within the sequence of eukaryotic protein-coding genes.