Viruses in which the envelope proteins have been replaced as described are referred to as pseudotyped viruses.
Most attempts to limit tropism have used chimeric envelope proteins bearing antibody fragments.
With this method, the foreign viral envelope proteins can be used to alter host tropism or an increased/decreased stability of the virus particles.
For example, pseudotyping allows to specify the character of the envelope proteins.
These envelope proteins transduce to all cell types.
In env, it is derived from the surface and transmembrane for the viral envelope protein.
The envelope proteins form small projections 5-10 nm long.
Both envelope proteins (E1 and E2) are highly glycosylated and important in cell entry.
In these cells the viral genes that encode envelope proteins have restricted expression.
A major difference between these two types of virions is their envelope proteins.