The results were independently confirmed by in situ hybridization of the endogenous genes at selected stages (data not shown).
We next tested whether expression of endogenous Hh-responsive genes was stimulated by the agonist.
In 1981, the first example of alternative splicing in a transcript from a normal, endogenous gene was characterized.
As such, the endogenous gene was used as a DNA loading reference representing two copies.
Genes from a genetically modified organism may pass to another organism just like an endogenous gene.
The technique of gene targeting uses homologous recombination to target desired changes to a specific endogenous gene.
This includes modification of endogenous genes.
This method creates a transgenic mouse and is used to insert new genetic information into the mouse genome or to over-express endogenous genes.
This could result in different expression patterns or could affect the function of other endogenous genes within the host.
Both transcriptional and post-transcriptional gene silencing are used to regulate endogenous genes.