Previous studies addressed the need for simpler tests and strategies to identify patients with a high probability of having PCP to initiate either empiric treatment or aggressive investigation [ 5 6 ] .
Susceptibility testing should be routine, with empiric antibiotic treatment guided by resistance patterns in the community in which the organism was acquired, pending the results.
Patients who are receiving a macrolide for MAC prophylaxis should never receive macrolide monotherapy for empiric treatment of bacterial pneumonia.
Master Quitrin and I have discussed empiric treatments since homeopathic remedies have proved ineffectual.
Summary Recommendations: When treatment of influenza is indicated in a patient with suspected influenza, health care providers should initiate empiric antiviral treatment as soon as possible.
Early empiric treatment with oseltamivir or zanamivir is recommended for all persons with suspected or confirmed influenza requiring hospitalization.
Early empiric treatment should be considered for persons with suspected or confirmed influenza who are at higher risk for complications, even if not hospitalized, including:
HIV-infected persons with genital ulcers or urethritis also should receive such empiric treatment, to decrease the load of excreted virus as quickly as possible.
In the UK, empiric treatment with amoxicillin is recommended as the first line for community-acquired pneumonia, with doxycycline or clarithromycin as alternatives.
Fluconazole should not be used for empiric treatment of fungemia because resistance of non-albicans Candida species to fluconazole has been reported (EIII).