Most patients respond well to L-dopa, which supplements the dopamine in the brain, but its effectiveness diminishes with time.

But their effectiveness is already diminishing.

Since the net momentum of the rod relative to the missile is roughly zero its effectiveness will rapidly diminish as the broken ring expands.

Tom Hume's effectiveness as a closer had diminished, and no other consistent relievers emerged.

In the later stages of the war, as the use of gas increased, its overall effectiveness diminished.

Golota fought back, however, and as the round drew to a close, Tyson's effectiveness was diminishing.

The effectiveness of PEP diminishes the longer after exposure it is initiated (12).

Their effectiveness would diminish even faster than the need for effectiveness increased.

Although the Boers continued to hit back when they could, once the armies were dispersed their effectiveness diminished greatly.

And, finally, it is important to remember that the effectiveness of the Holy Office diminished once one left the central valley.