Barstow refused to let anyone else try the fruit until its effect on Lazarus was established.
Of course, its effect on service users' welfare is not yet established.
Dietary effects on heart disease, cancer, and diabetes are established.
The effect is well established, but the mechanism is not well understood.
The beneficial effects of vigorous exercise on longevity have long been assumed but were not firmly established.
The scientists found that the effect is usually established within the first 2-3 weeks.
Thus, a causal effect between strategy efforts and these developments cannot be firmly established.
In 1970, the new system of state routes took effect and SR 512 was officially established.
The effect is well established with many theories to explain the effect but without a clear winner.
Once the causes and effects of any potential hazards have been established, the system being studied can then be modified to improve its safety.