The earliest grave marker with a death date is from 1807.

The earliest grave markers located in the cemetery date back to 1661.

"The watches are very early markers in that consumer electronics revolution."

He also laid down some early markers for the new legislative session.

The earliest extant markers date to 1798 and 1809.

It may be an early marker of the disease.

The first officer disliked violence, but he was familiar with many of its early markers.

The marker replaced the last of three earlier markers that vandals had previously destroyed.

She doubted the basophil spike was truly an early marker for the disease.

In the mid-1970's, he defined some early markers of melanoma, the most serious form of skin cancer.