One interesting possibility is that different start sites may be used at different points in the cell cycle or during cellular differentiation.
During differentiation the cells become specialized to perform various functions.
It is thought to function in neurite outgrowth and process elongation during neuronal differentiation.
Note: The subscripts outside the parenthesis indicate which variables are being held constant during differentiation.
However the topic result quite controversial since different reports described also a role for miR-124 during neuronal differentiation.
This shows that HDAC1 is required for cell fate determination during differentiation.
Thus either P100 levels are reduced or P100 becomes modified during differentiation.
Emx1 is present in practically all cortical neurons during proliferation, migration, differentiation and maturation.
Once a planet reaches sufficient mass, the materials with different densities segregate within, during planetary differentiation.
The cellular mechanism that occurs during aggregation and differentiation is still not fully studied.