This could include both direct and indirect binding as a part of binding to FKBP12.
E2F-6 mediates repression by direct binding to polycomb-group proteins or via the formation of a large multimeric complex containing Mga and Max proteins.
Cdk1-cyclin complexes are also governed by direct binding of Cdk inhibitor proteins (CKIs).
The most common mechanism of nuclear receptor action involves direct binding of the nuclear receptor to a DNA hormone response element.
This is through direct binding of miR-31 at its target site in the 3'UTR of FOXP3 mRNA.
ASF/SF2 accomplishes this regulation through direct or indirect binding to exonic splicing enhancer (ESE) sequences.
It binds directly to the androgen receptor, promoting transcriptional through direct binding to the androgen receptor FXXLF motif region.
The second process includes the direct binding of chromium(V), produced by reduction in the cell, and chromium(IV) compounds to the DNA.
One function of androgen receptor that is independent of direct binding to its target DNA sequence, is facilitated by recruitment via other DNA-binding proteins.
Trx inhibits ASK1 kinase activity by direct binding to its N-terminal coiled-coil domain (NCC).