Often poorly differentiated tumors do not display such characteristics, making the EM evaluation of little value.
Most FA's are well or moderately differentiated tumors, although high-grade, poorly differentiated variants have been described.
In patients with poorly differentiated tumors, myometrial invasion occurs much more frequently.
Special studies can help in differentiating more poorly differentiated tumors.
Often poorly differentiated tumors do not display such characteristics, and EM evaluation would be of little value.
A Gleason score of 8 to 10 means poorly differentiated tumors with cells that are likely to grow rapidly and spread to other parts of the body.
At 10 years, the prostate cancer-specific mortality rates were 8.3%, 9.1%, and 25.6% for men with well-differentiated, moderately differentiated, and poorly differentiated tumors, respectively.
However, undifferentiated benign tumors and differentiated malignant tumors can occur.
Clear stromal invasion is used to differentiate borderline tumors from malignant tumors.