Personal or family medical history or drugs a person is taking can give further diagnostic clues.

It leads to arterial hypertension (high blood pressure) associated with hypokalemia, usually a diagnostic clue.

Coupled with the gill flexibility this is a good diagnostic clue to species level.

The lack of response is an important diagnostic clue.

This increase has little adverse effect on the health, but is used as a diagnostic clue.

The character of the apex beat may provide vital diagnostic clues:

They have distinctive nicks, or notches on their free edges, that can be seen under a hand lens, a very good diagnostic clue to species.

Marked recent weight loss is a major clinical manifestation, and unresponsiveness of the ascites to diuretics is an additional diagnostic clue.

Overproduction of prolactin leads to cessation of menstrual periods and infertility, which may be a diagnostic clue.

The best diagnostic clue is a poorly marginated, mass-like enhancing soft tissue involving any area of the orbit.