Complete surgical excision with adequate surgical margins and assessment for the presence of detectable metastatic disease along with short- and long-term followup is standard.

Unless there is macroscopic, radiologically detectable disease it may be necessary to perform cytogenetic and immunohistochemical studies on biopsy specimens, possibly even obtained from laparotomy, to exclude lymphona.

Pretreatment factors that influence outcome include site and size of the primary tumor and presence or absence of clinically detectable metastatic disease.

Successful treatment generally requires the combination of effective systemic chemotherapy and complete resection of all clinically detectable disease.

Approximately 20% to 25% of patients with osteosarcoma present with clinically detectable metastatic disease.

The time from active infection to clinically detectable disease may make it difficult for epidemiologists to establish which partner was the source of infection.

Most of the patients studied were free of clinically detectable vascular disease.

It is not an easily detectable disease.

In immunocompetent individuals CMV infections are of chronic or latent type and are usually not associated with clinically detectable disease.

While many adult cases in the medical literature are associated with mental disorders, most patients with habit polydipsia have no other detectable disease.