Despite her handicap, Biffen learned to read, and later was able to write using her mouth.

The Reds had considerable experience with hominids, despite their handicap.

Spencer appears the most well-adjusted and calm of the three, despite his handicap.

Despite his handicap, he had an air of quiet confidence about him.

"If anything, I grew up with a superiority complex despite my handicap," he said.

Despite his handicap, Ostlund maintained many private interests, including playing the piano.

Despite his handicap, the director has created a new career as a lecturer and university professor.

Despite her handicap, she made phenomenal progress learning to communicate with the outside world.

She had a great deal of courage, participating in Talent Night, despite her handicap.

Despite her handicap, Pinky is determined to participate in the show.