deoxyribonucleotides

It is an intermediate in the metabolism of deoxyribonucleotides.

Deoxyribonucleotides are nucleotides in which the sugar is deoxyribose.

Deoxyribonucleotides in turn are used in the synthesis of DNA.

The reduction of ribonucleotides to deoxyribonucleotides is catalyzed by ribonucleotide reductase.

This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides.

The mechanism that is currently accepted for the reduction of ribonucleotides to deoxyribonucleotides is depicted in the following scheme.

Unlike the other deoxyribonucleotides, thymidine monophosphate does not contain the "deoxy" prefix in its name.

Hydrolyses both ribonucleotides and deoxyribonucleotides.

DNA ligase then joins the deoxyribonucleotides together, completing the synthesis of the lagging strand.

Gallo noted that virus replicated faster in an activated cell where deoxyribonucleotides are in plentiful supply.

Activated free deoxyribonucleotides exist in the cell as deoxyribonucleotide triphosphates (dNTPs).

DNA: A polymeric molecule made of deoxyribonucleotides, hence then name deoxyribonucleic acid.

There are several differences between DNA deoxyribonucleotides and RNA ribonucleotides.

Glutaredoxins function as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.

In ribonucleotides, the sugar component is ribose while in deoxyribonucleotides, the sugar component is deoxyribose.

During DNA synthesis, DNA polymerases must select against ribonucleotides, present at much higher levels compared with deoxyribonucleotides.

Hydroxyurea inhibits the rate-limiting enzyme supplying deoxyribonucleotides - ribonucleotide reductase - and substantially diminishes HIV replication.

Once dATP binds to ribonucleotide reductase, the overall catalytic activity of the enzyme decreases, as it signifies an abundance of deoxyribonucleotides.

The deoxyribonucleotides used to make DNA are made from ribonucleotides, the building blocks of RNA, by removing the 2'-hydroxyl group.

In these experiments, chromosome preparations are treated on the slide with DNase I, DNA polymerase I and radioactive deoxyribonucleotides.

Ribonucleotide reductase (RNR, also known as ribonucleoside diphosphate reductase) is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides.

In all known organisms, the deoxyribonucleotides that make up DNA are synthesized by the action of ribonucleotide reductase (RNR) enzymes on their corresponding ribonucleotides.

Two of the four deoxyribonucleotides and two of the four ribonucleotides, the respective building blocks of DNA and RNA, are purines.

Since the enzyme catalyses the de novo synthesis of deoxyribonucleotides (dNTPs), precursors to DNA synthesis, it is essential for cell proliferation.

Once RNR is inhibited, the cell cannot produce the deoxyribonucleotides required for DNA replication and repair, and cell apoptosis is induced.