Toluene was removed under vacuum and the crude mixture was purified by column chromatography (EtOAc: hexane, 1:49) to afford the product (22.6 mg, 75%) as a colorless oil.
A few decades ago, however, German scientists isolated a crude mixture of chemicals from the fruits that appeared to have liver-protectant properties and called the extract silymarin.
They were a crude mixture of ancient and modern.
This was while Charley Pemberton was selling the elixir, although a cruder mixture, under the name "Coca-Cola", all with his father's blessing.
It was here that he made his great discovery: that aniline could be partly transformed into a crude mixture which when extracted with alcohol produced a substance with an intense purple colour.
Their lyrics are often a crude mixture of German and English slang.
Gasoline (typically octane, 8 carbons linked together) is only part of the crude mixture.
'This is pure idiocy,' a voice from the other side of the thicket said in the crude mixture of Elene and Styric that identified the speaker as a Zemoch.
Phosgenation: Reaction of the isophorone diamine with phosgene to form a crude mixture containing IPDI conformers (25/75 cis/trans)
This can be used to remove americium from plutonium by melting the crude mixture together with salts such as sodium chloride.