The route makes a bend to the northeast and enters the hamlet of Limerick, where it crosses a junction with NY 12E.
NY 180 bends northeast again, crossing a junction with CR 128 and entering the town of Clayton.
The route crosses through another commercial section, crossing a junction with CR 16 (Horseblock Road).
The route passes multiple residential communities, crossing a junction with Mount Sinai-Coram Road.
The route changes little through North Buffalo, crossing multiple residential side streets and a junction with Kenmore Avenue.
The road continues south crossing the river and a junction (7) with the A62 autoroute.
They stop pedestrians and vehicles from crossing a junction where another thing has the right of way to cross.
A short distance later, the routes a small residential area and cross a junction with CR 11, which forks off again a short distance later.
After a couple of miles, the route crosses a junction with Stark Road and enters the hamlet of Raymondville.
A more fundamental issue was the intensive traffic over the M&KR section, crossing a junction of main roads at Coatbridge.