It is still uncertain whether adding progestin to the regimen to protect the uterus will also protect the breast against cancer or perhaps blunt the benefits of estrogen to the heart or is whether the estrogen patch will confer the cardiovascular benefits of a 50 percent reduction in coronary mortality associated with oral estrogens.
A relative risk reduction of 19% in coronary mortality was found in a meta-analysis of patients at all levels of risk.
The siesta habit has recently been associated with a 37% reduction in coronary mortality, possibly due to reduced cardiovascular stress mediated by daytime sleep.
He also noted that the Honolulu Heart Study showed a substantial decrease in coronary mortality among Japanese-American men who drank alcohol, "and what these men mostly drink is beer, not wine."
Siesta in healthy adults and coronary mortality in the general population.
In a meta-analysis of cholesterol-lowering trials published in the British Medical Journal in 1992, he demonstrated that coronary mortality was not lowered by cholesterol lowering, but total mortality was increased.
Antioxidant vitamin intake and coronary mortality in a longitudinal population study.
Neither Framingham nor four other major studies among thousands of people found that coffee drinking increased coronary mortality, even among patients with high blood pressure.