This is a considerable disadvantage to a real time systems designer.

"We will be at a considerable disadvantage in negotiating if our thoughts are open to him."

A lizard without its tail is at a considerable disadvantage.

Without luck, I would be operating at a considerable disadvantage.

Such firms would be at a considerable disadvantage to those providing universal service.

This asymmetry could put American businesses at a considerable disadvantage.

But it puts the remaining prosecutors at a considerable disadvantage.

Yet with such infrequent investigations, there is often considerable disadvantage for the schools and the children.

Picard would find himself at a considerable disadvantage, he reflected.

She is also hopelessly in love - a considerable professional disadvantage.