The lamellar bone begins forming soon after the collagen matrix of either tissue becomes mineralized.
Their distribution in the collagen matrix of the forming dentin suggests these proteins play an important role in the regulation of mineral deposition.
Chronic overuse of tendons leads to microscopic tears within the collagen matrix, which gradually weakens the tissue.
This mineralization of the collagen matrix stiffens it and transforms it into bone.
In fact, bone is a mineralized collagen matrix; if the mineral is dissolved out of bone, it becomes rubbery.
Increased water content and disorganized collagen matrix in tendon lesions may be detected by ultrasonography or magnetic resonance imaging.
A limitation (and obvious next step) to this study is that we do not have independent information about the integrity of the collagen matrix.
Over time, the wounded body tissue then overexpresses collagen inside the provisional matrix to create a collagen matrix.
His latest research has focused on the biomechanics of fibroblasts interacting with three dimensional collagen matrices.
Integrins have been identified on the upper shaft of the cilium, acting as anchors to the collagen matrix around it.