Dr. Chandra said this was not a clinically meaningful difference in birth weight.
Forty-six percent of participants had clinically meaningful pain relief with pot compared to 18% with placebo.
No clinically meaningful risk factor has been identified.
By his reckoning, only 3 of the 10 voting members of the committee were convinced that the drug was "clinically meaningful."
The two studies demonstrated no clinically meaningful or statistically significant placebo adjusted weight loss.
There was no difference found between longevity, symptoms, or any other clinically meaningful outcome.
Mepolizumab improved the quality of life, but the improvement was "not clinically meaningful," according to a reviewer.
There were no clinically meaningful effects when ramelteon was coadministered with any of these drugs.
But she said there was no "clinically meaningful" improvement in vision.
Initially, this development was not regarded by the medical profession as a clinically meaningful development.