The arrangement of cholesterol molecules in the bilayer is important for successful binding.

During the reaction, a cholesterol molecule is added to the C-terminus of SHH-N.

Also, salts attach themselves to cholesterol molecules in the bile to keep them from crystallizing.

In addition, LDL has a highly hydrophobic core consisting of polyunsaturated fatty acid known as linoleate and about 1500 esterified cholesterol molecules.

This is significant because the Cell membrane contains between 20% and 50% cholesterol molecules.

Both testosterone and estrogen, its female counterpart, are natural steroids that start out from a cholesterol molecule but then wander relatively far from each other chemically.

Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol.

These compounds have a hydroxyl- or a keto- group on the cholesterol molecule.

The unnatural cholesterol molecule that has also been synthesized is called ent-cholesterol.

Most importantly, the interior of the protein encompasses a 26 x 12 x 11-Angstrom hydrophobic tunnel that is apparently large enough to bind a single cholesterol molecule.