This trial will measure the effects of Vytorin vs. simvastatin alone in determining primary outcomes of cardiovascular and cerebrovascular events in 18,000 patients who have been hospitalized for an acute coronary syndrome.
Adverse effects in patients with dementia include an increased risk of mortality and cerebrovascular events, as well as metabolic effects, extrapyramidal symptoms, falls, cognitive worsening, cardiac arrhythmia, and pneumonia.
There are many possible side effects of boosting, including the occurrence of a cerebrovascular or cardiovascular event such as a stroke or heart attack.
Drugs and natural molecules which stabilize mast cell membrane and monoclonal antibodies that protect mast cell surface could emerge as novel therapeutic modalities capable of preventing acute coronary and cerebrovascular events [20].
If this does not improve the symptoms, atypical antipsychotics may offer an alternative, although they are effective against agitation only in the short-term while posing a well-documented risk of cerebrovascular events (e.g. stroke).
In a 2006 meta-analysis of randomized control studies, the cerebrovascular events associated with COX-2 inhibitors were examined, but no significant risks were found when compared to nonselective NSAIDs or placebos.
Patients suffering from vascular dementia present with cognitive impairment, acutely or subacutely, after an acute cerebrovascular event.
It will include prior cerebrovascular events, major diabetic complications, recent trauma or surgery, severe hypertension or any problem that might lead to major bleeding complications.
The presence of a patent foramen ovale should be considered as a possible cause of the cerebrovascular event, even though it may simply be an occasional finding in patients with cryptogenic stroke.
He was born in Boulogne-Billancourt, and died in Paris of a cerebrovascular event at age 74.