I caused great harm, heartache and difficulties for so many people.

Your brother wants me to tell you how very sorry he is for causing so much worry and heartache.

"Alcoholic physicians have already caused enough heartache in my life."

"We have all known of people who did not make a will causing family hardships and additional heartache."

The fewer people who knew of the drugs' existence the better - it was too easy to abuse them and had caused enough heartache.

While these might be signs of "progress" to some, they cause heartache to most Long Islanders.

Baker must lead his men through troubled times and make decisions that may result in the death of a paratrooper, which causes him much heartache.

Being treated unfairly at work may, quite literally, cause heartache.

Calvin does not want Leo to be back in their lives as he has caused heartache for his mother.

Things look good for a while, but somehow something breaks down between them, causing heartache, frustration, and loneliness.