The pressure over some of their body regions decreased or stopped the blood flow to the region causing pressure sores or gangrene.

The most severe cases can cause skin atrophy, ulceration and gangrene.

The leg wound he received caused gaseous gangrene, and Tarkovsky had to undergo six gradual amputations.

Continued smoking can cause gangrene and lead to amputation of the toes, feet or limbs.

The worms had caused torsion and gangrene of the ileum, which was interpreted as the cause of death.

If the circulation is further damaged by diabetes, the damage can be severe enough to cause gangrene.

In rare cases, it can cause gangrene.

In rare cases it can cause ulceration and ischemic gangrene.

Jewish and Muslim circumcision was claimed to cause gangrene, leading to fatalities.

They were punished by being handcuffed to cell bars for eight hours per day, until the cuffs had cut into their wrists and caused gangrene.